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Janet Kanini Ikua
Rank: Elder Joined: 3/2/2009 Posts: 26,330 Location: Masada
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tnai9 wrote:Cancer is a deadly disease and when your diagnosis is stage 4, there isn't much medically to be done and this cuts across all cancers because the cancer cells have spread to distant organs. Paliative care/end of life support is recommedned. But further, cancer in the vital organs is more deadly and as someone said, complications from chemo and reduced immunity(Chemo kills cancer cells and normal cells) is really a challenge. I lost a bro to cancer of the gall bladder early this year, he was diagnosed in stage 4 and passed on one month after diagnosis from an infection he picked after insertion of a stent in India. His liver and kidneys wouldn't withstand chemo and then experienced multiple organ failure(blood poisoning) coz the liver wasn't functioning. Oncologists in the country sometimes tell you the truth, like my bro they advised against the India trip, but family decided to try. Critically early diagnosis is very important, but its not possible in most cancers because cancer can affect any organ of the body. So how can this diagnosis be done? Is it possible to check all organs one by one plus all areas of the body? What are the early obvious signs? Portfolio: Sold You know you've made it when you get a parking space for your yatcht.
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Rank: Veteran Joined: 10/11/2009 Posts: 1,223
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Impunity wrote:Wororo wrote:Dahatre wrote:washiku wrote:So what is coming out is that if it hits Level 4 you are done? Like nothing really can change? You can never be healed completely? Pretty much if it is a tumor. Here are the stages: Stage 0=Abnormal cells are present but have not spread to nearby tissue. Also called carcinoma in situ, or CIS. CIS is not cancer, but it may become cancer. Stages I-III=Cancer is present. The higher the number, the larger the cancer tumor and the more it has spread into nearby tissues. Stage IV=The cancer has spread to distant parts of the body. Source True but some other forms simply have like two main stages. Stage 1 & 4 - because the transition between stages 1 & 4 is quite drastic due to its original attack organ eg liver. Liver cancer transition quite fast between the 4 stages since liver is a vital organ which receives lots of blood and the blood system is what cancer cells use to migrate/regroup. Liver is like a hub in this case. Anytime a cancer cell can be transferred to a different part of the body and start at one new cancer colony! Actually the cancer stages are defined by the size of the tumor and the potential of the cancer cells to be moved from an infected region of the body to unaffected region. Quite scary I must say. WHAT IS CANCER? In layman''s language please. Thanks Cancer is a collective term used to describe a group of different diseases that are characterized by the loss of control of cell growth and division, leading to a primary tumor that invades and destroys adjacent tissues. It may also spread to other regions of the body through a process known as metastasis, which is the cause of 90% of cancer deaths.Cancer remains one of the most difficult diseases to treat and is responsible for approximately 14.5% of all deaths worldwide. History will not remember you for your IQ. It will remember you for what you did. “Genius is 1 percent inspiration, 99 percent perspiration.” Thomas Edison
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Rank: Veteran Joined: 10/11/2009 Posts: 1,223
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EARLY DIAGNOSIS OF CANCER AND ITS THERAPEUTIC RELEVANCEThe high potential for mutation of tumor cells limits the usefulness of tissue biopsy as a standard prognostic procedure for cancer because, due to the genetic diversity within a single solid tumor, cells from one end may differ from those at the other and only some mutations are shared throughout the whole mass. Accordingly, a biopsy could miss mutations that might radically change the diagnosis and prognosis of a patient, and although it can provide data about specific mutations that might make a tumor vulnerable to targeted therapies, that information may become inaccurate as the cancer evolves. For an early diagnosis, prognosis, and epidemiology of cancer, it is necessary to detect specific biomarkers that, ideally, should be collected from biofluids such as blood or serum. Several genetic, epigenetic, proteomic, glycomic, and imaging biomarkers are currently used for cancer diagnosis and therapeutic monitoring, including: AFP (liver cancer), Bcr-Abl (chronic myeloid leukemia), BRCA1/BRCA2 (breast/ovarian cancer), BRAF V600E (melanoma/colorectal cancer), CA-125 (ovarian cancer), CA19-9 (pancreatic cancer), CEA (colorectal cancer), EGFR (non-small cell lung carcinoma), HER-2 (breast cancer), KIT (gastrointestinal stromal tumor), PSA (prostate cancer), S100 (melanoma).Although proteins are used in the clinic to diagnose illnesses and monitor people undergoing treatment, any of those used as cancer biomarkers are inaccurate. For example, prostate-specific antigen (PSA) can give false positives because this antigen can be elevated in blood for other reasons. Circulating DNA (ctDNA) in human blood, first reported in the blood of cancer patients in 1977, might perform better than proteins as a biomarker because it bears mutations that are hallmarks of cancer. Circulating tumor DNA is composed of genome fragments that are released when cancer cells die and float freely through the bloodstream, and it could be an excellent cancer biomarker. Unfortunately, ctDNA is not yet ready for a leading role in the clinic, mainly because the most sensitive techniques for its detection require some knowledge about which mutations to search for, and this is a laborious task that must be performed for each individual patient. One alternative is to use exome sequencing, which does not require a previous knowledge about the cancer but is prohibitively expensive. A focused approach to the therapy of lung cancer that would permit keeping costs low has been developed. This approach is based on the identification of a small fraction of the genome (0.004%) that is repeatedly mutated in these cancers. Because almost all patients with lung cancer have at least one mutation in these regions, these mutations may be found by sequencing this small fraction 10,000 times over. The method should work in almost every cancer, except in the case of brain cancers, in which the blood–brain barrier stops tumor DNA from reaching the bloodstream. Unfortunately, the potential of ctDNA as a cancer-screening tool is limited to advanced forms of cancer, which discharge relatively high levels of DNA, but it does not perform well for detecting early cancer forms. It is likely that molecular characterization of a given cancer will lead to the identification of different subsets of cancer disease with a different natural history, sensitivity, and resistance to treatment. In this task, efforts to develop, validate, and implement predictive biomarkers in clinical trials and eventually in routine care are important. History will not remember you for your IQ. It will remember you for what you did. “Genius is 1 percent inspiration, 99 percent perspiration.” Thomas Edison
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Rank: Veteran Joined: 12/4/2009 Posts: 1,982 Location: matano manne
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2012 wrote:Rahatupu wrote:New pain: in 2013 I lost a childhood buddy to stomach cancer and even posted the same here. Last month I lost a nephew to breastfeeding cancer and the pain and sadness is immense. The boy was 23 and hap lived with the lump on his left breast for a long time until it became painful around Dec 2016. Late Feb is when diagnosis was started and by the time the results were out he didn't survive for a week. My take: diagnosis is key. There's breastfeeding cancer? Does it get passed on to the baby? Sorry,must be this autocomplete thing. Meant breast cancer.
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Rank: Veteran Joined: 12/4/2009 Posts: 1,982 Location: matano manne
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tnai9 wrote:Cancer is a deadly disease and when your diagnosis is stage 4, there isn't much medically to be done and this cuts across all cancers because the cancer cells have spread to distant organs. Paliative care/end of life support is recommedned. But further, cancer in the vital organs is more deadly and as someone said, complications from chemo and reduced immunity(Chemo kills cancer cells and normal cells) is really a challenge. I lost a bro to cancer of the gall bladder early this year, he was diagnosed in stage 4 and passed on one month after diagnosis from an infection he picked after insertion of a stent in India. His liver and kidneys wouldn't withstand chemo and then experienced multiple organ failure(blood poisoning) coz the liver wasn't functioning. Oncologists in the country sometimes tell you the truth, like my bro they advised against the India trip, but family decided to try. Critically early diagnosis is very important, but its not possible in most cancers because cancer can affect any organ of the body. True. Early diagnosis is everything but the challenge is, there aren't symptoms that early enough. Like pain isn't felt until it's at stage 4. Like my nephew he didn't bother with the lump on his breast until it got painful. Then it was too late.
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Rank: Elder Joined: 2/22/2009 Posts: 2,449 Location: Africa
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Janet Kanini Ikua should be declared a national hero(ine).
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Rank: Veteran Joined: 12/4/2009 Posts: 1,982 Location: matano manne
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Shak wrote:Janet Kanini Ikua should be declared a national hero(ine). Eh boss why? Mafeelings.....
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Rank: Elder Joined: 10/4/2006 Posts: 13,822 Location: Nairobi
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Impunity wrote:
WHAT IS CANCER?
In layman''s language please. Thanks
cancer is when cells in parts of the body start to abnormally grow! so really... it's not a foreign object it's your body's cell reproduction malfunctioning. Why does it happen... well... i guess the list of things that may cause cancer is growing. if you ask me... it's always been with us. some are genetic and so we passed them around. some lipukad when we got to some certain age... for majority of humanity's time we never really got to these ages we are living and these numbers and so they show! some have environmental or dietary... has anyone ever seen this list?  I would invite intellectually curious people to examine the case of 'henrietta lacks'. Why does her cells behave the way they do? We have a lot of crap embedded in our dna and some just mutate and causes the body to behave in certain ways when the conditions are right! Do you know all that crap about generational curses? DNA!! All Mushrooms are edible! Some Mushroom are only edible ONCE!
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Rank: Veteran Joined: 9/11/2015 Posts: 1,024
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Shak wrote:Janet Kanini Ikua should be declared a national hero(ine). Umm, by whom? and why?
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Rank: Elder Joined: 8/4/2008 Posts: 2,849 Location: Rupi
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Impunity wrote:Euge wrote:washiku wrote:So what is coming out is that if it hits Level 4 you are done? Like nothing really can change? You can never be healed completely? Its the message that i get. Start parking and get ready to check out. In India the huzzy was told Janet had like between 6months to 5 years to live...she was strong enough and managed 2.5 years. I have never felt this sad in recent times...the last time I felt the same way was when Abgela Chibalonza passed on suddenly! Pole bro. This has really affected you. Let me look for the interview with Kiuna Lord, thank you!
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Rank: Veteran Joined: 10/11/2009 Posts: 1,223
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masukuma wrote:Impunity wrote:
WHAT IS CANCER?
In layman''s language please. Thanks
cancer is when cells in parts of the body start to abnormally grow! so really... it's not a foreign object it's your body's cell reproduction malfunctioning. Why does it happen... well... i guess the list of things that may cause cancer is growing. if you ask me... it's always been with us. some are genetic and so we passed them around. some lipukad when we got to some certain age... for majority of humanity's time we never really got to these ages we are living and these numbers and so they show! some have environmental or dietary... has anyone ever seen this list?  I would invite intellectually curious people to examine the case of 'henrietta lacks'. Why does her cells behave the way they do? We have a lot of crap embedded in our dna and some just mutate and causes the body to behave in certain ways when the conditions are right! Do you know all that crap about generational curses? DNA!! As any other scientist i still have a microfuge tube with HeLa cells somewhere in the freezer. History will not remember you for your IQ. It will remember you for what you did. “Genius is 1 percent inspiration, 99 percent perspiration.” Thomas Edison
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Rank: Elder Joined: 2/8/2013 Posts: 4,068 Location: At Large.
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Euge wrote:Impunity wrote:Euge wrote:washiku wrote:So what is coming out is that if it hits Level 4 you are done? Like nothing really can change? You can never be healed completely? Its the message that i get. Start parking and get ready to check out. In India the huzzy was told Janet had like between 6months to 5 years to live...she was strong enough and managed 2.5 years. I have never felt this sad in recent times...the last time I felt the same way was when Abgela Chibalonza passed on suddenly! Pole bro. This has really affected you. Let me look for the interview with Kiuna Where can one get the interview with Kiuna? Love is beautiful and so are those who share it.With Love, Marriage is an amazing event in ones life time, the foundation of joy, happiness and success.
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Rank: Elder Joined: 8/4/2008 Posts: 2,849 Location: Rupi
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Bigchick wrote:Euge wrote:Impunity wrote:Euge wrote:washiku wrote:So what is coming out is that if it hits Level 4 you are done? Like nothing really can change? You can never be healed completely? Its the message that i get. Start parking and get ready to check out. In India the huzzy was told Janet had like between 6months to 5 years to live...she was strong enough and managed 2.5 years. I have never felt this sad in recent times...the last time I felt the same way was when Abgela Chibalonza passed on suddenly! Pole bro. This has really affected you. Let me look for the interview with Kiuna Where can one get the interview with Kiuna? Janet's Interview with Kathy KiunaLord, thank you!
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Rank: Elder Joined: 12/7/2012 Posts: 11,921
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Euge wrote:Bigchick wrote:Euge wrote:Impunity wrote:Euge wrote:washiku wrote:So what is coming out is that if it hits Level 4 you are done? Like nothing really can change? You can never be healed completely? Its the message that i get. Start parking and get ready to check out. In India the huzzy was told Janet had like between 6months to 5 years to live...she was strong enough and managed 2.5 years. I have never felt this sad in recent times...the last time I felt the same way was when Abgela Chibalonza passed on suddenly! Pole bro. This has really affected you. Let me look for the interview with Kiuna Where can one get the interview with Kiuna? Janet's Interview with Kathy Kiuna Wow just tooo saaad   In the business world, everyone is paid in two coins - cash and experience. Take the experience first; the cash will come later - H Geneen
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Rank: Member Joined: 6/17/2010 Posts: 572
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BGL wrote:masukuma wrote:Impunity wrote:
WHAT IS CANCER?
In layman''s language please. Thanks
cancer is when cells in parts of the body start to abnormally grow! so really... it's not a foreign object it's your body's cell reproduction malfunctioning. Why does it happen... well... i guess the list of things that may cause cancer is growing. if you ask me... it's always been with us. some are genetic and so we passed them around. some lipukad when we got to some certain age... for majority of humanity's time we never really got to these ages we are living and these numbers and so they show! some have environmental or dietary... has anyone ever seen this list?  I would invite intellectually curious people to examine the case of 'henrietta lacks'. Why does her cells behave the way they do? We have a lot of crap embedded in our dna and some just mutate and causes the body to behave in certain ways when the conditions are right! Do you know all that crap about generational curses? DNA!! As any other scientist i still have a microfuge tube with HeLa cells somewhere in the freezer. @BGL, is there anyone doing research on the effects of Autophagy, fasting/intermittent fasting, zero carb diet on cancer? 'One headache for famous medieval holy people was that someone might murder you to acquire your body parts for the relics trade'
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Rank: Elder Joined: 3/2/2009 Posts: 26,330 Location: Masada
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Angelica _ann wrote:Euge wrote:Bigchick wrote:Euge wrote:Impunity wrote:Euge wrote:washiku wrote:So what is coming out is that if it hits Level 4 you are done? Like nothing really can change? You can never be healed completely? Its the message that i get. Start parking and get ready to check out. In India the huzzy was told Janet had like between 6months to 5 years to live...she was strong enough and managed 2.5 years. I have never felt this sad in recent times...the last time I felt the same way was when Abgela Chibalonza passed on suddenly! Pole bro. This has really affected you. Let me look for the interview with Kiuna Where can one get the interview with Kiuna? Janet's Interview with Kathy Kiuna Wow just tooo saaad   Now you know why that day I first saw the kiuna video with I cried. It's really sad. From this video you could see things were really rolling down fast. Go with peace babe,I loved you so much. Portfolio: Sold You know you've made it when you get a parking space for your yatcht.
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Rank: Elder Joined: 10/4/2006 Posts: 13,822 Location: Nairobi
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vky wrote:BGL wrote:masukuma wrote:Impunity wrote:
WHAT IS CANCER?
In layman''s language please. Thanks
cancer is when cells in parts of the body start to abnormally grow! so really... it's not a foreign object it's your body's cell reproduction malfunctioning. Why does it happen... well... i guess the list of things that may cause cancer is growing. if you ask me... it's always been with us. some are genetic and so we passed them around. some lipukad when we got to some certain age... for majority of humanity's time we never really got to these ages we are living and these numbers and so they show! some have environmental or dietary... has anyone ever seen this list?  I would invite intellectually curious people to examine the case of 'henrietta lacks'. Why does her cells behave the way they do? We have a lot of crap embedded in our dna and some just mutate and causes the body to behave in certain ways when the conditions are right! Do you know all that crap about generational curses? DNA!! As any other scientist i still have a microfuge tube with HeLa cells somewhere in the freezer. @BGL, is there anyone doing research on the effects of Autophagy, fasting/intermittent fasting, zero carb diet on cancer? Well... Steve Jobs was into fasts and zero cabs diets and sh*t like eating carrots and apples. he was vegan! so... here is the thing we know so far... EARLY DIAGNOSIS WORKS! try to live a sane life and eat well, exercise but get checked often. All Mushrooms are edible! Some Mushroom are only edible ONCE!
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Rank: Elder Joined: 8/4/2008 Posts: 2,849 Location: Rupi
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Impunity wrote:Angelica _ann wrote:Euge wrote:Bigchick wrote:Euge wrote:Impunity wrote:Euge wrote:washiku wrote:So what is coming out is that if it hits Level 4 you are done? Like nothing really can change? You can never be healed completely? Its the message that i get. Start parking and get ready to check out. In India the huzzy was told Janet had like between 6months to 5 years to live...she was strong enough and managed 2.5 years. I have never felt this sad in recent times...the last time I felt the same way was when Abgela Chibalonza passed on suddenly! Pole bro. This has really affected you. Let me look for the interview with Kiuna Where can one get the interview with Kiuna? Janet's Interview with Kathy Kiuna Wow just tooo saaad   Now you know why that day I first saw the kiuna video with I cried. It's really sad. From this video you could see things were really rolling down fast. Go with peace babe,I loved you so much. I have just watched on youtube. I hadn't seen it before. She had lost alot of weight. I forgot to check when the interview was done. Rest easy Janet Lord, thank you!
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Rank: Elder Joined: 2/26/2012 Posts: 15,980
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I dont know if this will be appropriate if posted on this thread but since there are so many cancer threads and this one seems to be the live one. I will just post and admin and move it as she pleases. New* scientific information alertThe (American) National Cancer Institute believes that Asprin can reduce cancer risk. Quote:In the United States, tens of millions of adults take aspirin to reduce their risk of heart attack or stroke. But studies over the last two decades have suggested that regular use of aspirin may have another important benefit: decreasing the risk of developing or dying from some types of cancer.
Results from some of these studies, in fact, formed the basis for guidance released in April 2016Exit Disclaimer by an influential federal advisory panel on disease prevention. The panel, the U.S. Preventive Services Task Force (USPSTF), recommended that, for some people, aspirin can be used to help reduce their risk of cardiovascular disease and colorectal cancer.
Several researchers who conducted some of the seminal studies on which the USPSTF based its guidance stressed the importance of the panel’s actions.
Writing in Nature Reviews Cancer, Andrew Chan, M.D., of Harvard Medical School, and several colleagues called the recommendation a "crucial first step in realizing a potential broader population-wide impact of aspirin use" for cancer prevention.
The USPSTF recommendations are far from sweeping, however. And researchers are continuing to investigate critical questions, including just how aspirin may reduce colorectal cancer risk and what other cancers, if any, regular use of this century-old drug may help to prevent.
The findings from these studies should help to fill an important informational void. At least one study suggests that, even before the USPSTF made its recommendations, Americans were buying in to the idea of aspirin's anticancer potential; in that 2015 study, 18% of Americans who were taking aspirin regularly said they were doing so to help prevent cancer. More hereCNN 3/4/2017Quote:(CNN)An aspirin a day may keep the doctor away. It may also reduce your chances of dying from cancer, according to a study on long-term regular aspirin use and different kinds of cancer.
Yin Cao, an instructor in the Medicine, Clinical and Translational Epidemiology Unit at Massachusetts General Hospital and Harvard Medical School, presented the information Monday at the American Association for Cancer Research meeting in Washington. Cao looked at data from over 86,000 women who were part of the Nurses' Health Study between 1980 and 2012 and over 43,000 men who were part of the Health Professionals Follow-Up Study from 1986 to 2012.
Over that 32-year period, over 8,200 women and nearly 4,600 men died of cancer. The risk of death overall was 7% lower for women and 11% for men who took aspirin regularly, compared with those who did not. The risk of dying from cancer was 7% lower for women and 15% lower for men who took aspirin regularly, compared with those who didn't take a regular dose. The strongest connection was with colorectal cancer: There was a 31% lower risk for women and 30% for men who were among regular aspirin takers, as other studies have showed. But it also lowered women's risk of dying from breast cancer by 11% and men's risk of dying from prostate cancer by 23%. Men's risk of dying from lung cancer was also lower. Evidence has been accumulating very rapidly showing aspirin works in reducing cancer and cardiovascular disease mortality," Cao said. "It is good to remember, though, if a person wants to take a low-dose aspirin, especially if a person has had cancer, they will want to have an initial conversation with their doctor first."
Not everyone can take aspirin, particularly if you are at high risk for ulcers and gastrointestinal bleeding. Studies have showed an increased risk of both when taking a daily aspirin, but the benefit does outweigh the risk for most other people.
"There are only two emotions in the market, hope & fear. The problem is you hope when you should fear & fear when you should hope: - Jesse Livermore .
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Rank: Member Joined: 6/26/2008 Posts: 365
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Impunity wrote:I have never felt this sad in recent times...the last time I felt the same way was when Abgela Chibalonza passed on suddenly! I feel you. I have never felt so sad in recent times as well. If you have only one smile in you, give it to the people you love - Maya Angelou
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