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HIV Cure now in sight
Rahatupu
#41 Posted : Wednesday, August 14, 2013 1:33:19 PM
Rank: Veteran

Joined: 12/4/2009
Posts: 1,982
Location: matano manne
mkenyan wrote:
guru267 wrote:
Don't most AIDS patients die of one cancer or another? I believe we can kill two birds with one stone here!

One documentary I watched talks about how marijuana is hated by pharmaceuticals because of its ability to cure countless diseases in its natural form all the way from the common cold to cancer... Legalizing it would put them out of business completely!

As a result of marijuana prohibition, research on its healing capabilities is zero at best!

coincidentally many people die of cancer nowadays....
.

Business will surely kill a good portion of humanity for a long time. Remember the resistance to Generic antivirals?
kiterunner
#42 Posted : Friday, August 23, 2013 2:08:33 AM
Rank: Member

Joined: 7/9/2011
Posts: 730
Location: Nairobi
murchr wrote:
[quote=jguru][quote=kiterunner]A Kenyan pharmacist has cured HIV using methotrexate by using a cancer drug that kills the special cells that habour the HIV virus. The work has not been published and i hope it ll be published soon. I wonder if Dr Barasa is our BGL

http://www.nation.co.ke/.../-/wr8ii7z/-/index.html[/quote]

Maybe BGL = Dr Simon Barasa Situma...

I read that story in the papers, and I need to see the published results before I can appreciate what's going on.


Notice he went under after u mentioned that? Anyway, another DN writer writes about UNIPRON

http://www.nation.co.ke/...50/-/6vxw7/-/index.html[/quote]


@BGL please update us on the Baraza work, thank you
our goals are best achieved indirectly
kiterunner
#43 Posted : Tuesday, August 27, 2013 12:46:08 PM
Rank: Member

Joined: 7/9/2011
Posts: 730
Location: Nairobi
Dr Barasa at it again, now more people on his study

http://www.nation.co.ke/.../-/sqfkbdz/-/index.html


Apparently he is having a hard time having his work accepted out there.
our goals are best achieved indirectly
pariah
#44 Posted : Sunday, September 01, 2013 1:58:42 AM
Rank: Member

Joined: 11/24/2011
Posts: 833
@bgl come back
BGL
#45 Posted : Sunday, September 01, 2013 3:12:09 AM
Rank: Veteran

Joined: 10/11/2009
Posts: 1,223
Well, i want to see the publication but before i can comment on this trending topic. However, i see he did present this work in some online conference page 14 but it is the first time i am hearing of the conference and none of the top dogs in the game presented anything http://targetmeeting.com/files/pdf/handbook49.pdf

However, cure means different things to different people. The tendency has been to classify patients with undetectable viral loads without ARVs over a period of time as cured. What the common mwananchi is not told is that some HIV exists as reservoirs in lymphoid tissues but in peripheral blood and you can only detect that by PCR and sampling peripheral blood is just not convincing enough.

On this debate i think this Barasa Situma is not just alone...... the market seems to be full of this sensational reporting which is just bad science. I will give an example...... In March this year during the CROI conference (2013) a researcher from University of Missisipi reported cure of a baby born to HIV infected mother but put on a cocktail of drugs a few hours after birth. On this one i did not agree just like many scientists since the presenter did not prove the baby was infected in the first place.
Secondly on the berlin patient case is straight forward......... he got a bone marrow transplant from a donor with delta32CCR5. For those reading this post a person with delta32CCR5 is resistant to infection by HIV utilizing the CCR5 coreceptor to infect the cell.

Parting shot: Barasa Situma........ give us more data and conclusive data.
History will not remember you for your IQ. It will remember you for what you did. “Genius is 1 percent inspiration, 99 percent perspiration.” Thomas Edison
Meduza
#46 Posted : Friday, September 13, 2013 2:26:14 PM
Rank: Member

Joined: 2/7/2013
Posts: 447
Location: Nairobi
http://mrcvs.co.uk/en/ne...-clears-HIV-in-primates
You cant win, unless you first begin....
murchr
#47 Posted : Saturday, September 14, 2013 7:37:34 AM
Rank: Elder

Joined: 2/26/2012
Posts: 15,980
BGL wrote:
There are so many conspiracy theorists in the market place about the origins of HIV BUT the biggest of all is Dr. Leonard Horowitz and Prof. Jakob Segal. The arguments of Prof Segal which is exactly what @ murchr is pointing at have to be considered together with an argument on the origin of SIV (cousin of HIV) in green monkeys. In real life scenario, chapter 6 of kenyan constitution should be read with other chapters not in isolation.

Now back to @ Murchr, Our bodies (mine and yours) harbour viral DNA acquired millions of years ago. For instance,i will give two examples (i) common cold is caused by a rhino virus but is not lethal (ii) Herpes simplex virus just wakes up one day and causes an ugly watery blister on your mouth and may stay silent for years before it pops up to cause more damage without killing the host.

I agree with the author that HIV is different. As you know, HIV attacks the 'army' and by army i mean CD4+ T cells and macrophages, whose work is to protect the cells. Ever wondered why we do not have a vaccine against HIV yet? because the virus is much clever than us. We actually need to change strategy on how to design our vaccines because the current strategies cause even more damage. In some cases the vaccine may even lead to new infection in experimental group compared to the placebo (control) group. The vaccine is safe on its own (how vaccines against HIV are designed is a discussion for another day). The reason why the group receiving the vaccine may be at risk is that the vaccine will activate the cells to finish off the virus when it is infecting the body BUT HIV infects with ease these activated cells. These are the questions we need to ask these people but i have no problems with development of vaccines.

On your last question, @ Murchr i am not an oncologist but since i suppose i had some good training in bio-medical sciences i will just comment. We got two types of cells: (i) Germ cells (sperms & ova) (ii) Somatic cells (any other cells not germ cells kama vile cells making the skin, bones, macho etc etc). Lifestyles do influence and expose our somatic cells to all sorts of stress and this may lead to cancer. Mutations on germ cells are so dangerous since can be passed on to the next generation while mutations on somatic cells are not. Just another reason why you should protect your makende at all time.


Quote:
“Although the drug is available in local pharmacies on prescription, it must never be used without clear instruction from your doctors,” says Dr Barasa.

The lecturer has since applied for a patent with the Kenya Industrial Property Institute for the treatment process, titled Cure for HIV/Aids Virus.

“Our methodology is simple, safe, acceptable, and cheap, although not yet scientifically validated,” says Dr Barasa in his case study. Even though we could not verify the claims, Dr Barasa says two patients, a man aged 29 and a woman aged 40, both of whom had previously been diagnosed with HIV and put on antiretroviral medication, “are now functionally cured”.

“We treated them with methotrexate, which works by suppressing rapid expansion of the specialised stem cells in the bone marrow, called hematopoietic cells,” he says.

The treatment consists of a combination of agents that are given in a methodology that is tailored to suit individual patients with continuous laboratory monitoring by Pathologist Lancet Kenya Limited, a fully-fledged reference laboratory situated in Nairobi’s Upper Hill area that boasts a wide test menu, including sophisticated molecular tests.


https://churchill.co.ke/...d-cured-of-hiv-in-kenya

@BGL your view please
"There are only two emotions in the market, hope & fear. The problem is you hope when you should fear & fear when you should hope: - Jesse Livermore
.
BGL
#48 Posted : Sunday, September 15, 2013 3:39:11 PM
Rank: Veteran

Joined: 10/11/2009
Posts: 1,223
murchr wrote:
BGL wrote:
There are so many conspiracy theorists in the market place about the origins of HIV BUT the biggest of all is Dr. Leonard Horowitz and Prof. Jakob Segal. The arguments of Prof Segal which is exactly what @ murchr is pointing at have to be considered together with an argument on the origin of SIV (cousin of HIV) in green monkeys. In real life scenario, chapter 6 of kenyan constitution should be read with other chapters not in isolation.

Now back to @ Murchr, Our bodies (mine and yours) harbour viral DNA acquired millions of years ago. For instance,i will give two examples (i) common cold is caused by a rhino virus but is not lethal (ii) Herpes simplex virus just wakes up one day and causes an ugly watery blister on your mouth and may stay silent for years before it pops up to cause more damage without killing the host.

I agree with the author that HIV is different. As you know, HIV attacks the 'army' and by army i mean CD4+ T cells and macrophages, whose work is to protect the cells. Ever wondered why we do not have a vaccine against HIV yet? because the virus is much clever than us. We actually need to change strategy on how to design our vaccines because the current strategies cause even more damage. In some cases the vaccine may even lead to new infection in experimental group compared to the placebo (control) group. The vaccine is safe on its own (how vaccines against HIV are designed is a discussion for another day). The reason why the group receiving the vaccine may be at risk is that the vaccine will activate the cells to finish off the virus when it is infecting the body BUT HIV infects with ease these activated cells. These are the questions we need to ask these people but i have no problems with development of vaccines.

On your last question, @ Murchr i am not an oncologist but since i suppose i had some good training in bio-medical sciences i will just comment. We got two types of cells: (i) Germ cells (sperms & ova) (ii) Somatic cells (any other cells not germ cells kama vile cells making the skin, bones, macho etc etc). Lifestyles do influence and expose our somatic cells to all sorts of stress and this may lead to cancer. Mutations on germ cells are so dangerous since can be passed on to the next generation while mutations on somatic cells are not. Just another reason why you should protect your makende at all time.


Quote:
“Although the drug is available in local pharmacies on prescription, it must never be used without clear instruction from your doctors,” says Dr Barasa.

The lecturer has since applied for a patent with the Kenya Industrial Property Institute for the treatment process, titled Cure for HIV/Aids Virus.

“Our methodology is simple, safe, acceptable, and cheap, although not yet scientifically validated,” says Dr Barasa in his case study. Even though we could not verify the claims, Dr Barasa says two patients, a man aged 29 and a woman aged 40, both of whom had previously been diagnosed with HIV and put on antiretroviral medication, “are now functionally cured”.

“We treated them with methotrexate, which works by suppressing rapid expansion of the specialised stem cells in the bone marrow, called hematopoietic cells,” he says.

The treatment consists of a combination of agents that are given in a methodology that is tailored to suit individual patients with continuous laboratory monitoring by Pathologist Lancet Kenya Limited, a fully-fledged reference laboratory situated in Nairobi’s Upper Hill area that boasts a wide test menu, including sophisticated molecular tests.


https://churchill.co.ke/...d-cured-of-hiv-in-kenya

@BGL your view please


Read post 45 and you will find my response.
History will not remember you for your IQ. It will remember you for what you did. “Genius is 1 percent inspiration, 99 percent perspiration.” Thomas Edison
Siringi
#49 Posted : Sunday, December 01, 2013 5:32:39 AM
Rank: Elder

Joined: 6/8/2013
Posts: 2,517
Marking the day Sukari iliingia sumu

World AIDS day with Franco Attention na SIDA

"😖😡KQ makes money for everyone except the shareholder 😏😏 " overheard in Wazua
Gordon Gekko
#50 Posted : Wednesday, December 04, 2013 2:21:50 PM
Rank: Elder

Joined: 5/27/2008
Posts: 3,760
@pariah, this is not curative, but preventative, so your heading is misleading.

http://www.jstor.org/stable/1183010
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